About Rejwin

A herbal and Ayurvedic formulation for supportive care

Ayurvedic Proprietary Formulation for Cancer Care

Rejwin is a thoughtfully developed herbal and Ayurvedic formulation designed to provide comprehensive supportive care alongside conventional cancer treatment. It is formulated to support the body’s natural defence mechanisms, maintain physiological balance, and promote systemic wellness during the cancer-care journey.

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Rejwin, an Ayurvedic proprietary formulation

Rejwin is an Ayurvedic Proprietary Formulation that, with its multi-dimensional approach, is intended to support healthy immune function, antioxidant defences, tissue integrity, and overall vitality. It may also help support the body in managing treatment-related stress and maintaining quality of life during chemotherapy and radiation therapy.

Rejwin is designed as an adjunctive Ayurvedic formulation to support the body’s natural response to processes associated with tumour growth, invasion and vascularisation. It should be used as part of an integrated care plan that may include medical treatment, balanced nutrition, physical activity, adequate rest, emotional support and regular clinical monitoring.

Rejwin is an Ayurvedic supportive-care formulation developed to complement conventional cancer treatment. It supports immune health, antioxidant defences, tissue integrity and overall vitality while helping the body maintain balance during the cancer-care journey. Designed for integrated use alongside appropriate medical care, nutrition, rest and clinical monitoring, Rejwin supports a patient-centred approach to well-being without replacing prescribed oncology treatment.

Why a multi-target approach matters?

Cancer biology involves several overlapping mechanisms. A formulation that focuses only on antioxidant activity, only on immunity or only on inflammation may not adequately represent the complexity of the cancer-care environment.

Rejwin is based on a broader supportive framework:

Oxidative stress + inflammation + immune balance + nutrition + cellular wellness + vitality

These areas are interconnected. Oxidative stress may affect inflammatory signalling; inflammation may influence immune and metabolic function; poor nutrition may reduce resilience; and reduced vitality may affect recovery and quality of life. Rejwin's intended value lies in bringing these supportive dimensions together in one formulation, while maintaining appropriate scientific, regulatory and clinical boundaries.

How Rejwin Addresses the Hallmarks of Cancer?

Developed with high scientific rigour, Rejwin is formulated with a multi-targeted Phyto-complex designed to target key biological vulnerability pathways in tumour growth. Rejwin has been designed around the principle that cancer-associated biology is multifactorial. Its supportive concept is based on addressing several areas of physiological importance rather than claiming to act through one isolated pathway.

Oxidative-stress support

Oxidative stress occurs when the production of reactive molecules exceeds the body’s antioxidant defences. Excessive oxidative stress may contribute to cellular damage, inflammation and impaired physiological balance. Rejwin is intended to provide antioxidant support that may help the body manage oxidative challenges and protect normal cellular functions.

Inflammation-management support

Persistent, uncontrolled inflammation may affect tissue health, immune signalling and metabolic balance. Rejwin's supportive approach includes ingredients selected for their traditional and scientifically investigated potential to support a balanced inflammatory response.

Immune-system support

A healthy immune system plays an important role in surveillance, recovery and protection against internal and external stressors. Rejwin aims to support immune resilience and general host defence through nutritional and herbal support.

Cellular-protection support

Cellular health depends on balanced antioxidant defences, adequate nutrition, normal metabolism, effective repair processes and appropriate elimination of damaged cells. Rejwin is positioned as a supportive formulation for maintaining these fundamental aspects of health.

Metabolic and nutritional support

Cancer and its treatment may affect appetite, digestion, nutrient intake, energy levels and body weight. Rejwin is intended to support nutritional well-being and overall vitality as part of a comprehensive care plan.

Support for tissue and microenvironment balance

The tissue environment around abnormal cells can influence inflammation, oxidative stress, immune activity and cellular communication. Rejwin's multi-component design is intended to support systemic balance rather than target only one aspect of this environment.

Recovery and quality-of-life support

Cancer care may be physically and emotionally demanding. By supporting general vitality, digestive comfort, nutritional status and resilience, Rejwin may be used as part of an individualized supportive-care program.

Re-establishing Apoptosis (Programmed Cell Death)

Cancer cells evade apoptosis by downregulating pro-apoptotic effectors and overexpressing anti-apoptotic proteins. Rejwin restores natural cell death through the intrinsic mitochondrial pathway:
  • Upregulation of Pro-Apoptotic Markers: Increases expressions of p53, BAX, BAD, and DNA double-strand break marker.
  • Downregulation of Survival Signals: Suppresses Bcl-xL (anti-apoptotic member).
  • Mitochondrial Permeabilization: Triggers Cytochrome-C release into the cytosol, activating the caspase cascade (Caspase-3, 8, 9, 10) to initiate clean, non-inflammatory and cell clearance.

Anti-Angiogenesis (Starving the Tumour)

Without vascularization, microscopic tumours remain dormant due to lack of oxygen and nutrients. Rejwin inhibits tumour angiogenesis by targeting key growth factors and enzymes:
  • VEGF-A Suppression: Significantly reduces Vascular Endothelial Growth Factor A (VEGF-A), cutting off signals for endothelial capillary sprouting.
  • MMP-2 & MMP-9 Downregulation: Suppresses Matrix Metalloproteinases (MMP-2 and MMP-9), preventing extracellular matrix degradation and blocking endothelial and cancer cell invasion.

Cell Cycle Arrest & Anti-Proliferation

Rejwin arrests the tumour cell cycle at the S-G2/M transition phase, halting DNA synthesis and preventing unchecked mitosis.

Key benefits of Rejwin

Rejwin is intended to offer supportive benefits within an integrated care and wellness plan.

Antioxidant support

Supports the body's natural antioxidant defence system and helps maintain normal cellular protection against oxidative stress.

Immune resilience

Provides nutritional and herbal support for normal immune function and physiological resilience.

Inflammation balance

Supports a healthy inflammatory response and overall systemic balance.

Cellular wellness

Helps support normal cellular health, metabolic balance and protection from everyday physiological stress.

Energy and vitality

Supports general strength, vitality and day-to-day well-being.

Holistic supportive care

Provides a multi-dimensional approach that can be incorporated into a broader plan involving medical treatment, nutrition, physical activity, sleep, psychological support, and regular clinical monitoring.

  • Provide an adjunctive Ayurvedic formulation to help inhibit tumour growth, invasion and vascularization.
  • Help reduce chemotherapy and radiation-induced toxicities, supporting overall quality of life during treatment.
  • Maintain immune health, systemic antioxidant defences and tissue integrity.

Core benefits

Inhibits Tumour Growth & Proliferation

Suppresses unchecked cell division and induces targeted apoptosis in malignant cells.

Anti-Angiogenic Action

Reduces pro-angiogenic factors (VEGF-A, MMP-2, MMP-9), helping to restrict the supply of blood and nutrients to tumour tissues.

Antioxidant & Free-Radical Scavenging

Neutralizes reactive oxygen species (ROS) to protect healthy cells from oxidative stress and DNA damage.

Supplementary Support

Fits alongside standard oncology therapies (chemotherapy/radiation) to help manage side effects like fatigue, loss of appetite, and systemic weakness.

Non-Toxic to Healthy Tissues

Pre-clinical studies demonstrate high selectivity for malignant cells without damaging healthy organ systems.

Composition

Botanical Phyto-constituents with Studied Anticancer Activity

Certain traditional botanicals contain naturally occurring compounds that have been investigated in laboratory and preclinical studies for effects on cancer-cell proliferation, oxidative stress, inflammation, immune signalling, angiogenesis, and apoptosis.

Noni Fruit (Morinda citrifolia)

Noni Fruit — Morinda citrifolia

Noni fruit contains anthraquinones such as damnacanthal, along with scopoletin, iridoids, coumarins, flavonoids, and polysaccharides. Research reviews note that noni preparations and damnacanthal have been studied for apoptosis-related and anti-proliferative activity in cancer models. Source

  • Damnacanthal: An anthraquinone studied for caspase-mediated apoptosis and effects associated with p53 signalling.
  • Scopoletin: A coumarin investigated for inhibition of cell proliferation and cell-cycle arrest in G0/G1 and S phases.
  • Iridoids: Studied for antioxidant activity and support in reducing oxidative stress.
  • Polysaccharides: Investigated for immunomodulatory activity, including activation of immune cells and immune-signalling pathways.
Lakshman Phala / Soursop (Annona muricata)

Lakshman Phala / Soursop — Annona muricata

Soursop, also called graviola, contains annonaceous acetogenins, flavonoids, and polyphenols. Its acetogenins—particularly annonacin—have been widely studied for mitochondrial and apoptotic effects in cancer-cell models. Source

  • Annonaceous acetogenins: Studied for interference with cellular ATP production and cancer-cell energy metabolism.
  • Annonacin: Investigated for mitochondrial apoptosis, ROS-related stress, cytochrome-c release, and activation of caspase-9 and caspase-3 in experimental systems.
  • Acetogenins: Reported in preclinical studies to increase pro-apoptotic Bax and reduce anti-apoptotic Bcl-2.
  • Flavonoids and polyphenols: Studied for antioxidant, anti-inflammatory, and apoptosis-supporting activity.
Kumuda (Nymphaea alba)

Kumuda — Nymphaea alba

White water lily contains phenolic acids, flavonoids, and alkaloids, including gallic acid, ellagic acid, quercetin, kaempferol, apigenin, nupharine, and nymphaeine. These constituents have been studied individually for antioxidant, anti-proliferative, and apoptosis-related activity.

  • Gallic acid: Studied for cytotoxic activity and inhibition of tumour-associated blood-vessel formation.
  • Ellagic acid: Known for antioxidant activity and investigated for cellular defence against oxidative damage.
  • Quercetin: Studied for inhibition of cancer-cell division.
  • Kaempferol: Investigated for suppression of proliferation and metastatic behaviour in experimental models.
  • Apigenin: Studied for promotion of apoptosis.
  • Flavonoid mixture: Investigated for effects on hormone-driven breast-cancer cell growth.
  • Phenolic acids: Support antioxidant protection against oxidative cellular damage.
Palasha (Butea monosperma)

Palasha — Butea monosperma

Palash, or Flame of the Forest, is a source of chalcone flavonoids, especially butein, along with butrin, isobutrin, butin, and coreopsin. Butein has been reviewed for broad preclinical biological activity, including antioxidant, anti-inflammatory, and anticancer properties. Source

  • Butein: The principal studied chalcone; investigated for apoptosis induction, inhibition of proliferation, and suppression of tumour growth, migration, and invasion in multiple preclinical cancer models.
  • Butrin: Studied for induction of colorectal cancer-cell death.
  • Butein and angiogenesis: Reported to suppress VEGF-induced endothelial-cell proliferation and migration.
  • Flower flavonoids: Studied for antioxidant and chemopreventive potential.
Putranjivaka (Putranjiva roxburghii)

Putranjivaka — Putranjiva roxburghii

Putranjiva contains flavonoids, tannins, phenolic acids, triterpenes, saponins, and glucosinolates. Its studied constituents include kaempferol, quercetin, rutin, tannic acid, ellagic acid, and gallic acid.

  • Kaempferol: Investigated for reduction of oxidative DNA damage and support of apoptosis in cancer cells.
  • Rutin: Studied for antioxidant and anti-inflammatory effects.
  • Triterpenes and saponins: Investigated for effects on cancer-cell membranes and cellular signalling.
  • Tannic acid: Studied for cytotoxic and apoptosis-promoting activity.
  • Mitochondrial activity: Certain extracts have been reported to disrupt mitochondrial function in liver-cancer cell models.
Simarouba (Simarouba glauca)

Simarouba — Simarouba glauca

Simarouba, also known as Paradise Tree or Lakshmitaru, contains quassinoids including glaucarubinone, glaucarubin, glaucarubol, glaucarubolone, ailanthinone, and holacanthone.

  • Glaucarubinone: Studied for cytotoxic activity against oral cancer, leukaemia, and other cancer-cell lines.
  • Glaucarubin and glaucarubol: Investigated for induction of cancer-cell death.
  • D-erythro-sphinganine: Studied for effects on cell-cycle regulation and cell migration.
Lodhra (Symplocos racemosa)

Lodhra — Symplocos racemosa

Lodhra contains symplocosides, beta-carboline alkaloids, flavonoids, and triterpenes, including quercetin, oleanolic acid, and ursolic acid.

  • Symplocosides: Studied for anti-angiogenic activity by reducing formation of tumour-supporting blood vessels.
  • Loturine, collutrine, and loturidine: Beta-carboline alkaloids associated with reported cytotoxic and anticancer activity.
  • Quercetin: Investigated for G1-phase cell-cycle arrest and caspase-mediated apoptosis.
  • Oleanolic acid and ursolic acid: Studied for suppression of cancer-cell survival pathways.
Haridra (Curcuma longa)

Haridra — Curcuma longa

Turmeric contains curcuminoids, principally curcumin, demethoxycurcumin, and bisdemethoxycurcumin. Curcumin is among the most extensively studied plant-derived compounds for effects on inflammation, oxidative stress, and cancer-cell signalling.

  • Curcumin: Studied for inhibition of cancer-cell proliferation, induction of apoptosis, and modulation of multiple tumour-growth signalling pathways.
  • Demethoxycurcumin and bisdemethoxycurcumin: Associated with anti-inflammatory activity.
  • Curcuminoids: Investigated for apoptosis-inducing activity in prostate-cancer cell models.
Jeevanti (Leptadenia reticulata)

Jeevanti — Leptadenia reticulata

Jeevanti contains flavonoids, phenolic acids, phytosterols, and triterpenes, including luteolin, apigenin, quercetin, kaempferol, rutin, ferulic acid, beta-sitosterol, stigmasterol, alpha-amyrin, and beta-amyrin.

  • Luteolin: Studied for antioxidant and anti-inflammatory activity, apoptosis induction, and inhibition of cancer-cell survival signalling.
  • Apigenin: Investigated for apoptosis and cell-cycle arrest.
  • Rutin: Studied for protection against oxidative DNA damage.
  • Ferulic acid: Investigated for reduction of inflammation-associated tumour promotion.
Kanchanara (Bauhinia variegata)

Kanchanara — Bauhinia variegata

Kanchanara contains flavonoids, anthocyanidin glycosides, and phytosterols, including kaempferol, quercetin, rutin, quercitrin, lupeol, stigmasterol, and beta-sitosterol.

  • Kaempferol: Studied for apoptosis, cell-cycle arrest, and reduced PI3K/Akt signalling.
  • Quercetin: Investigated for increased Bax and cleaved caspase-3/9 activity, with reduced anti-apoptotic Bcl-2.
  • Anthocyanidin glycosides: Studied for inhibition of cancer growth and spread in experimental systems.

The studies above were carried out on individual plant compounds in laboratory and preclinical models. They describe what has been researched about these botanicals, not proven effects of Rejwin in people. Rejwin is a supplement to, not a substitute for, treatment prescribed by your doctor.

Unique Ways of Rejwin

Patented Herbal Formulation

Backed by a granted Indian Patent, "A Method and Composition for Preparation of Herbal Solution for Cancer Treatment".

Scientifically & Pre-Clinically Validated

Tested across 14 malignant cell lines and multiple In-vivo models.

Targeted Dual Action

Combines pro-apoptotic activity (restoring natural cell death in malignant cells) with anti-angiogenic action (inhibiting new blood vessel growth towards malignant tumours).

High Safety & Selectivity Index

Selective toward malignant cells with minimal toxicity to healthy tissues, as demonstrated in toxicology testing.

Quality Certifications

Manufactured in perpetual AYUSH-licensed facilities License No. AUS-862, with GMP and ISO 9001:2015 quality certifications.

Complete Traceability

Produced under a strictly controlled farm-to-product manufacturing model.

Multi-target supportive formulation

Rejwin is designed to support several areas of wellness: including antioxidant defence, immune resilience, inflammation balance, cellular health, nutrition and vitality; rather than presenting a single-pathway concept.

Cancer-care support without replacement claims

The product is positioned as an adjunctive wellness formulation. It does not claim to replace oncology treatment, allowing the communication to remain responsible and patient-centred.

Science-informed product concept

The formulation concept is aligned with contemporary understanding of cancer biology, including oxidative stress, inflammation, immune evasion, altered metabolism, cellular survival and the tumour microenvironment.

Holistic patient-support orientation

Rejwin considers the person beyond the tumour by focusing on general strength, nutritional support, resilience, and quality of life.

Herbal and ayurvedic positioning

The product combines the traditional relevance of herbal support with the structured approach of ayurvedic product development, quality evaluation, standardization and responsible communication.

Designed for integrated care

Rejwin can be considered as part of a broader care strategy involving the treating oncologist, dietitian, pharmacist, Ayurvedic physician and other qualified healthcare professionals.

Who may consider Rejwin?

Rejwin may be considered for adults seeking nutritional and herbal support during the cancer-care journey, subject to professional advice and individual suitability.

It may be relevant for:

  • Individuals undergoing cancer treatment who require supportive nutritional planning.
  • Individuals in recovery who wish to support general vitality.
  • Individuals seeking antioxidant and immune-supportive wellness care.
  • Caregivers looking for a structured supportive-care product.
  • Health professionals developing an integrated wellness plan for suitable patients.

Disclaimer

Rejwin is an herbal and ayurvedic supportive-care product intended to support general wellness, antioxidant defence, immune function, nutritional status and vitality. It is not intended to diagnose, treat, cure or prevent cancer or any other disease. Rejwin is not a replacement for surgery, chemotherapy, radiotherapy, immunotherapy, targeted therapy, hormonal therapy or any treatment prescribed by a qualified healthcare professional.

Cancer care is a journey that requires medical expertise, nutritional attention, emotional support and informed personal care. Rejwin has been developed with a multi-target supportive philosophy to help address important aspects of overall wellness; including antioxidant protection, immune resilience, inflammation balance, cellular health, nutrition and vitality. With responsible use, professional guidance, and continued medical supervision, Rejwin may form part of an integrated supportive-care approach focused on helping individuals maintain strength and well-being throughout their cancer-care journey.

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